The book is filled with stories of people used as research participants, sometimes without their knowledge, sometimes with ill-informed consent, sometimes because of their inability to understand (i.e. patients with mental illness or prisoners).

Describe one scene from the book that deals with consent and how clinicians of the time handled it.
Do you think clinicians and researchers of the past had a fundamentally different view of people than they do today?
What does this book tell us about the history of medical research, and how medical research has (and has not) progressed since the 1950s? After reading this book, what do you think are key factors that influence medical research today?